12/05/2025
Two years is a long time, however, if you notice things are changing and behavior is escalating, getting it managed earlier than later would possibly take a little less time. 
Dog Aging Project Peer-Reviewed Study - “Dogs with consistent C*D💧 use showed a decline in the intensity of aggressive behaviors over time compared to a more steady trend among non-use dogs. […] The decline in the intensity of aggressive behaviors suggests the potential use of C*D in dog training. Further studies are needed to advance our understanding of this novel supplement at the mechanistic, clinical, and population levels.”
C*D has shown real promise in supporting dogs with anxiety, reactivity, and aggression. However, access to high-quality C*D is limited in many regions, and regulations vary widely across the U.S. and globally. For families who cannot access C*D or want a more standardized, long-term solution, GABA-producing calming probiotics offer a powerful, fully legal alternative with growing scientific support for dogs.
A 2025 randomized, placebo-controlled clinical trial found that dogs given a patented GABA-producing probiotic strain (Lactiplantibacillus plantarum LP815™) experienced significant reductions in aggression and anxiety, along with improved sleep stability and faster post-separation calming. No serious adverse effects were reported across more than 1,100 doses, making it a safe option for extended daily use.
Want to explore a science-backed probiotic🦠 option for your dog comment BETTERBELLY and we’ll send you more info.