10/23/2024
Did you know there is a new genetic disorder, linked in American Quarter Horses?
❗️Equine Juvenile Spinocerebellar Ataxia (EJSCA) is an inherited neurologic disease that causes ataxia in foals.❗️
🟥Phenotype: Affected foals develop ataxia, or incoordination, between 1 and 4 weeks of age. The disorder progresses within a few days until affected foals are unable to stand without assistance.
🟥Mode of Inheritance: Autosomal recessive
🟥Alleles: N = Normal/Unaffected, JSA = juvenile spinocerebellar ataxia
Explanation of results:
• Horses with N/N genotype will not have equine juvenile spinocerebellar ataxia and will not transmit the JSA allele to their offspring.
• Horses with N/JSA genotype will not have equine juvenile spinocerebellar ataxia, but are carriers. They may transmit the JSA allele to 50% of their offspring. Breedings between two carriers result in a 25% chance of producing an EJSCA-affected foal.
• Horses with JSA/JSA genotype will have juvenile spinocerebellar ataxia.
More info can be found at :https://vgl.ucdavis.edu/test/equine-juvenile-spinocerebellar-ataxia-ejsca