09/10/2026
This is Gravy and he has spina bifida. He has no problems getting around, but he is incontinent (f***l and urinary). He wears a diaper, as do his fellow bulldogs, Meatloaf and Spice. He likes playing with the other dogs, hanging out with his humans, taking long naps (often with his good friend Mr. Poole, a Maine C**n cat), and posing for photos with various monsters. What is spina bifida? This is a failure of the left and right vertebral arches (the top part of the vertebra) to fuse during embryological development. Sometimes it is just the bones that are not fusing entirely at the top, in which case there may be no clinical signs (seen as incidental finding when getting radiographs for something else). In other cases, either the meninges (covering of the cord) or the meninges with the end of the spinal cord will traverse through the opening and end up stuck to the underside of the skin, rather than traveling backwards towards the tail. Sometimes, fat from around the cord and nerve roots will accompany the meninges or spinal cord along this abnormal route. Historically, it was thought that this was a finite condition. In other words, whatever neurologic deficits are present around the time of birth are what the puppy is stuck with, and there will be no progression of disease. In recent years, this has been shown to be untrue in some cases. Neurologic deficits often include incontinence and weakness of the back legs. Some puppies have been shown to worsen neurologically as they grow. This happens in children with the same disorder. The spinal cord is tethered to soft tissues (often the underside of the skin) and the bones grow faster than the spinal cord/nerve roots. As the patient grows, this tethering pulls on the spinal cord, making the condition worse. Neurologic improvement following untethering the cord surgically has been documented in multiple cases. One of the figures below is from an article I coauthored with Patrick Roynard (a fellow neurologist and friend). It shows CT images of spina bifida at the end of the vertebral column. The other figure is a sagittal (side view) MRI image of a bulldog puppy with spina bifida. The abnormal tissue (circled on the left-hand image) traversing towards the skin is bright. On this sequence, this could be spinal fluid, fat, or a combination. On the middle image, the fat signal is suppressed. Since it is still bright, it is consistent with spinal fluid. On the right-hand image, a sequence is used to suppress free fluid (like spinal fluid). The material is dark, further supporting a diagnosis of a meningocele (a diverted sac of the meninges containing spinal fluid).