10/13/2026
WHAT IF WHEN YOU SPAY OR NEUTER YOUR DOG MATTERS JUST AS MUCH AS WHETHER YOU DO IT?
LINK TO STUDY
https://www.sciencedirect.com/science/article/pii/S1090023326003862?via%3Dihub&fbclid=IwY2xjawU7RqJleHRuA2FlbQIxMABwZG9mBWJyaWQRMXJJdTVLcXk1c1ZlcWdDYjZzcnRjBmFwcF9pZBAyMjIwMzkxNzg4MjAwODkyAAEeK88vVWruXQrtik6b4L-qwWEuEc0Ler0ZP0frzdp9-m7-oEmjBOqDoWwysZY_aem_NzvAkjbQn9o2hRidbqp9Xw
Preventing unwanted litters matters. But is it time to rethink HOW we sterilize dogs? Hormone-sparing procedures, including hysterectomy and vasectomy, can prevent reproduction while preserving natural s*x hormones.
π¬ NEW 2026 PEER-REVIEWED RESEARCH
Over 10 years, researchers reviewed records from 56,254 veterinary patients, including 313 dogs with mast cell tumors and 638 tumor-free comparison dogs. The study was accepted for publication in The Veterinary Journal.
π€― 1. TIMING MATTERS!
Dogs spayed or neutered before age 2 had 343% higher odds of a mast cell tumor diagnosis compared with intact dogs. Dogs sterilized after age 2 showed no statistically significant increase.
π 2. SIZE MATTERS!
Compared with small dogs, medium dogs had 2.6 times the odds and large dogs 5.2 times the odds.
βοΈ 3. WEIGHT MATTERS!
Overweight dogs had 80% higher odds than dogs at an ideal weight.
𧬠4. BREED MATTERS!
Compared with mixed-breed dogs, American Pit Bull Terriers had 7.5 times the odds and Boxers 3.9 times. Some breed groups were small.
β€οΈ 5. WHAT ABOUT SURVIVAL?
Neutering status wasnβt significantly associated with survival after surgery. Tumor grade and size were more important predictors.
π¬ WHY MIGHT HORMONES MATTER?
S*x hormones influence immune function and development. Researchers propose that early hormone removal and changes in luteinizing hormone (LH) may play a role, but this remains unproven.
πΎ THE BIG TAKEAWAY
Preventing unwanted litters doesnβt always mean removing hormone-producing organs. Itβs time for individualized conversations with veterinarians about WHEN and HOW we sterilize dogs.