02/13/2026
🚨Plusieurs médicaments régulièrement utilisés en médecine vétérinaire ont des impacts non négligeables sur le microbiome. Il faut savoir les utiliser consciemment & intelligemment🧐
Medication usage is a known contributor to the inter-individual variability of the gut microbiome. However, medications are often used repeatedly and for long periods, a notion yet unaccounted for in microbiome studies. A recent study by a team of Estonian researchers showed that not only the usage of antibiotics and antidepressants at sampling, but also past consumption, is associated with the gut microbiome. This effect can be “additive” - the more a medication is used, the stronger the impact on the microbiome. By utilizing retrospective medication usage data from electronic health records, they systematically evaluated the long-term effects of antibiotics and human-targeted medications on the gut microbiome. The research showed that past usage of medications is associated with the gut microbiome. For example, the effects of antibiotics, psycholeptics, antidepressants, proton pump inhibitors, and beta-blockers are detectable several years after use. Furthermore, by analyzing a sub cohort with a second micro biome characterization, they revealed that similar changes in the gut microbiome occur after treatment initiation or discontinuation, possibly indicating causal effects.